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The autophagy-resistant Mycobacterium tuberculosis Beijing strain upregulates KatG to evade starvation-induced autophagic restriction

Mycobacterium tuberculosis utilizes several mechanisms to block phagosome–lysosome fusion to evade host cell restriction. However, induction of host cell autophagy by starvation was shown to overcome this block, resulting in enhanced lysosomal delivery to mycobacterial phagosomes and the killing of...

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Detalles Bibliográficos
Autores principales: Siregar, Tegar Adriansyah Putra, Prombutara, Pinidphon, Kanjanasirirat, Phongthon, Kunkaew, Nawapol, Tubsuwan, Alisa, Boonmee, Atsadang, Palaga, Tanapat, Khumpanied, Tanawadee, Borwornpinyo, Suparerk, Chaiprasert, Angkana, Utaisincharoen, Pongsak, Ponpuak, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829027/
https://www.ncbi.nlm.nih.gov/pubmed/35038342
http://dx.doi.org/10.1093/femspd/ftac004