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The GSK-3 Inhibitor CT99021 Enhances the Acquisition of Spatial Learning and the Accuracy of Spatial Memory

Glycogen synthase kinase 3 (GSK-3) is a Ser/Thr protein kinase that regulates many cellular processes, including synaptic plasticity. Previously, we reported that inhibition of GSK-3 prevents the induction of one of the major forms of synaptic plasticity, N-methyl-D-aspartate receptor (NMDAR)-depend...

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Detalles Bibliográficos
Autores principales: Lee, Yeseul, Bortolotto, Zuner A., Bradley, Clarrisa A., Sanderson, Thomas M., Zhuo, Min, Kaang, Bong-Kiun, Collingridge, Graham L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829050/
https://www.ncbi.nlm.nih.gov/pubmed/35153671
http://dx.doi.org/10.3389/fnmol.2021.804130