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Molecular and in vivo phenotyping of missense variants of the human glucagon receptor
Naturally occurring missense variants of G protein–coupled receptors with loss of function have been linked to metabolic disease in case studies and in animal experiments. The glucagon receptor, one such G protein–coupled receptor, is involved in maintaining blood glucose and amino acid homeostasis;...
Autores principales: | van der Velden, Wijnand J.C., Lindquist, Peter, Madsen, Jakob S., Stassen, Roderick H.M.J., Wewer Albrechtsen, Nicolai J., Holst, Jens J., Hauser, Alexander S., Rosenkilde, Mette M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829087/ https://www.ncbi.nlm.nih.gov/pubmed/34801547 http://dx.doi.org/10.1016/j.jbc.2021.101413 |
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