Cargando…

The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis

Pseudomonas aeruginosa is an opportunistic human pathogen and a leading cause of chronic infection in the lungs of individuals with cystic fibrosis. After colonization, P. aeruginosa often undergoes a phenotypic conversion to mucoidy, characterized by overproduction of the alginate exopolysaccharide...

Descripción completa

Detalles Bibliográficos
Autores principales: Gheorghita, Andreea A., Wolfram, Francis, Whitfield, Gregory B., Jacobs, Holly M., Pfoh, Roland, Wong, Steven S.Y., Guitor, Allison K., Goodyear, Mara C., Berezuk, Alison M., Khursigara, Cezar M., Parsek, Matthew R., Howell, P. Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829089/
https://www.ncbi.nlm.nih.gov/pubmed/34990713
http://dx.doi.org/10.1016/j.jbc.2021.101560