Rapid, accurate mapping of transgene integration in viable rhesus macaque embryos using enhanced-specificity tagmentation-assisted PCR

Genome engineering is a powerful tool for in vitro research and the creation of novel model organisms and has growing clinical applications. Randomly integrating vectors, such as lentivirus- or transposase-based methods, are simple and easy to use but carry risks arising from insertional mutagenesis...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryu, Junghyun, Chan, William, Wettengel, Jochen M., Hanna, Carol B., Burwitz, Benjamin J., Hennebold, Jon D., Bimber, Benjamin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829455/
https://www.ncbi.nlm.nih.gov/pubmed/35211637
http://dx.doi.org/10.1016/j.omtm.2022.01.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829455/
https://www.ncbi.nlm.nih.gov/pubmed/35211637
http://dx.doi.org/10.1016/j.omtm.2022.01.009

Ejemplares similares