Transcriptional Analysis of Total CD8(+) T Cells and CD8(+)CD45RA(-) Memory T Cells From Young and Old Healthy Blood Donors

Memory CD8(+) T cells accumulate with aging, while the naïve T cell compartment decreases, leading to an increased susceptibility to infections and a decreased vaccine efficiency. To get deeper insights into the underlying mechanisms, this study aims to determine the age-dependent expression profile...

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Detalles Bibliográficos
Autores principales: Toma, Georgiana, Lemnian, Ioana Maria, Karapetian, Eliza, Grosse, Ivo, Seliger, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829550/
https://www.ncbi.nlm.nih.gov/pubmed/35154123
http://dx.doi.org/10.3389/fimmu.2022.806906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829550/
https://www.ncbi.nlm.nih.gov/pubmed/35154123
http://dx.doi.org/10.3389/fimmu.2022.806906

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