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Transcriptional Analysis of Total CD8(+) T Cells and CD8(+)CD45RA(-) Memory T Cells From Young and Old Healthy Blood Donors

Memory CD8(+) T cells accumulate with aging, while the naïve T cell compartment decreases, leading to an increased susceptibility to infections and a decreased vaccine efficiency. To get deeper insights into the underlying mechanisms, this study aims to determine the age-dependent expression profile...

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Detalles Bibliográficos
Autores principales:	Toma, Georgiana, Lemnian, Ioana Maria, Karapetian, Eliza, Grosse, Ivo, Seliger, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829550/ https://www.ncbi.nlm.nih.gov/pubmed/35154123 http://dx.doi.org/10.3389/fimmu.2022.806906

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