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Rexinoids Modulate Effector T Cell Expression of Mucosal Homing Markers CCR9 and α4β7 Integrin and Direct Their Migration In Vitro

Altering T cell trafficking to mucosal regions can enhance immune responses towards pathogenic infections and cancers at these sites, leading to better outcomes. All-trans-retinoic acid (ATRA) promotes T cell migration to mucosal surfaces by inducing transcription of the mucosal-homing receptors CCR...

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Detalles Bibliográficos
Autores principales: Manhas, Kavita R., Marshall, Pamela A., Wagner, Carl E., Jurutka, Peter W., Mancenido, Michelle V., Debray, Hannah Z., Blattman, Joseph N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829570/
https://www.ncbi.nlm.nih.gov/pubmed/35154092
http://dx.doi.org/10.3389/fimmu.2022.746484