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The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model

Dysbiosis-related perturbations in bile acid (BA) metabolism were observed in inflammatory bowel disease (IBD) patients, which was characterized by increased levels of sulfated BAs at the expense of secondary BAs. However, the exact effects of sulfated BAs on the etiology of IBD are not investigated...

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Detalles Bibliográficos
Autores principales: van der Lugt, Benthe, Vos, Maartje C.P., Grootte Bromhaar, Mechteld, Ijssennagger, Noortje, Vrieling, Frank, Meijerink, Jocelijn, Steegenga, Wilma T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829581/
https://www.ncbi.nlm.nih.gov/pubmed/35169646
http://dx.doi.org/10.1016/j.heliyon.2022.e08883