Enzymatic approaches for profiling cytosine methylation and hydroxymethylation

BACKGROUND: In mammals, modifications to cytosine bases, particularly in cytosine-guanine (CpG) dinucleotide contexts, play a major role in shaping the epigenome. The canonical epigenetic mark is 5-methylcytosine (5mC), but oxidized versions of 5mC, including 5-hydroxymethylcytosine (5hmC), are now...

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Detalles Bibliográficos
Autores principales: Wang, Tong, Loo, Christian E., Kohli, Rahul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829811/
https://www.ncbi.nlm.nih.gov/pubmed/34375743
http://dx.doi.org/10.1016/j.molmet.2021.101314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829811/
https://www.ncbi.nlm.nih.gov/pubmed/34375743
http://dx.doi.org/10.1016/j.molmet.2021.101314

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