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Electrochemical [4 + 1] Tandem sp(3)(C–H) Double Amination for the Direct Synthesis of 3-Acyl-Functionalized Imidazo[1,5-a]pyridines

[Image: see text] 3-Acyl imidazo[1,5-a]pyridines, featured pharmaceutical moieties that were prepared by a three-step reaction conventionally, could be obtained in one step by an electrochemical tandem sp(3) (C–H) double amination of acetophenones with pyridine ethylamines using ammonium iodide as a...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Yao, Xia, Xu, Xian-jing, Zhang, Shuai, Ren, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829863/
https://www.ncbi.nlm.nih.gov/pubmed/35155923
http://dx.doi.org/10.1021/acsomega.1c06029