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HPV-mediated regulation of SMAD4 modulates the DNA damage response in head and neck cancer

BACKGROUND: Head and Neck cancer (HNC) is a fatal malignancy with poor prognosis. Human Papillomavirus (HPV) infection is becoming the prominent cause of HNC in the western world, and studying the molecular mechanisms underlying its action in cancers is key towards targeted therapy. To replicate, HP...

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Detalles Bibliográficos
Autores principales: Citro, Simona, Miccolo, Claudia, Medda, Alessandro, Ghiani, Lavinia, Tagliabue, Marta, Ansarin, Mohssen, Chiocca, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830113/
https://www.ncbi.nlm.nih.gov/pubmed/35144669
http://dx.doi.org/10.1186/s13046-022-02258-9