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HPV-mediated regulation of SMAD4 modulates the DNA damage response in head and neck cancer
BACKGROUND: Head and Neck cancer (HNC) is a fatal malignancy with poor prognosis. Human Papillomavirus (HPV) infection is becoming the prominent cause of HNC in the western world, and studying the molecular mechanisms underlying its action in cancers is key towards targeted therapy. To replicate, HP...
Autores principales: | Citro, Simona, Miccolo, Claudia, Medda, Alessandro, Ghiani, Lavinia, Tagliabue, Marta, Ansarin, Mohssen, Chiocca, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830113/ https://www.ncbi.nlm.nih.gov/pubmed/35144669 http://dx.doi.org/10.1186/s13046-022-02258-9 |
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