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ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells

The antineoplastic activity of pre-transplant regimens in hematopoietic stem cell transplantation (HSCT) is a critical factor for acute myeloid leukemia (AML) patients. There is an urgent need to identify novel approaches without jeopardizing patient safety. We hypothesized that combination of drugs...

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Detalles Bibliográficos
Autores principales: Valdez, Benigno C., Murray, David, Yuan, Bin, Nieto, Yago, Popat, Uday, Andersson, Borje S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830224/
https://www.ncbi.nlm.nih.gov/pubmed/35154579
http://dx.doi.org/10.18632/oncotarget.28193