Molecular Architecture of the Antiophidic Protein DM64 and its Binding Specificity to Myotoxin II From Bothrops asper Venom

DM64 is a toxin-neutralizing serum glycoprotein isolated from Didelphis aurita, an ophiophagous marsupial naturally resistant to snake envenomation. This 64 kDa antitoxin targets myotoxic phospholipases A(2), which account for most local tissue damage of viperid snakebites. We investigated the nonco...

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Detalles Bibliográficos
Autores principales: Soares, Barbara S., Rocha, Surza Lucia G., Bastos, Viviane A., Lima, Diogo B., Carvalho, Paulo C., Gozzo, Fabio C., Demeler, Borries, Williams, Tayler L., Arnold, Janelle, Henrickson, Amy, Jørgensen, Thomas J. D., Souza, Tatiana A. C. B., Perales, Jonas, Valente, Richard H., Lomonte, Bruno, Gomes-Neto, Francisco, Neves-Ferreira, Ana Gisele C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830425/
https://www.ncbi.nlm.nih.gov/pubmed/35155563
http://dx.doi.org/10.3389/fmolb.2021.787368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830425/
https://www.ncbi.nlm.nih.gov/pubmed/35155563
http://dx.doi.org/10.3389/fmolb.2021.787368

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