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Epithelial Ablation of Miro1/Rhot1 GTPase Augments Lung Inflammation by Cigarette Smoke

Mitochondrial quality control is sustained by Miro1 (Rhot1), a calcium-binding membrane-anchored GTPase during mitophagy. The exact mechanism that operates the interaction of Miro1 with mitophagy machinery and their role in cigarette smoke (CS)-induced mitochondrial dysfunction that often results in...

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Detalles Bibliográficos
Autores principales: Sharma, Shikha, Wang, Qixin, Muthumalage, Thivanka, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830451/
https://www.ncbi.nlm.nih.gov/pubmed/35366248
http://dx.doi.org/10.3390/pathophysiology28040033