A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage

A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed. While leukocyte elastase’s (HLE) role has been documented, the...

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Detalles Bibliográficos
Autores principales: Patterson, Eric K., Vanin Moreno, Nicolas, Fraser, Douglas D., Cepinskas, Gediminas, Iida, Takaya, Berard, Roberta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830470/
https://www.ncbi.nlm.nih.gov/pubmed/35366277
http://dx.doi.org/10.3390/pathophysiology28030021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830470/
https://www.ncbi.nlm.nih.gov/pubmed/35366277
http://dx.doi.org/10.3390/pathophysiology28030021

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