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Towards Structure-Guided Development of Pain Therapeutics Targeting Voltage-Gated Sodium Channels
Voltage-gated sodium (Na(V)) channels are critical molecular determinants of action potential generation and propagation in excitable cells. Normal Na(V) channel function disruption can affect physiological neuronal signaling and lead to increased sensitivity to pain, congenital indifference to pain...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830516/ https://www.ncbi.nlm.nih.gov/pubmed/35153801 http://dx.doi.org/10.3389/fphar.2022.842032 |