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Towards Structure-Guided Development of Pain Therapeutics Targeting Voltage-Gated Sodium Channels

Voltage-gated sodium (Na(V)) channels are critical molecular determinants of action potential generation and propagation in excitable cells. Normal Na(V) channel function disruption can affect physiological neuronal signaling and lead to increased sensitivity to pain, congenital indifference to pain...

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Detalles Bibliográficos
Autores principales:	Nguyen, Phuong T., Yarov-Yarovoy, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830516/ https://www.ncbi.nlm.nih.gov/pubmed/35153801 http://dx.doi.org/10.3389/fphar.2022.842032

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