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Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups

Pulmonary vascular remodeling (PVR) in utero results in the development of heart failure. The alterations that occur in cardiac lipid and mitochondrial bioenergetics during the development of in utero PVR was unknown. In this study, PVR was induced in pups in utero by exposure of pregnant dams to in...

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Detalles Bibliográficos
Autores principales: Cole, Laura K., Sparagna, Genevieve C., Dolinsky, Vernon W., Hatch, Grant M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830687/
https://www.ncbi.nlm.nih.gov/pubmed/35143544
http://dx.doi.org/10.1371/journal.pone.0263520