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SCClone: Accurate Clustering of Tumor Single-Cell DNA Sequencing Data
Single-cell DNA sequencing (scDNA-seq) enables high-resolution profiling of genetic diversity among single cells and is especially useful for deciphering the intra-tumor heterogeneity and evolutionary history of tumor. Specific technical issues such as allele dropout, false-positive errors, and doub...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830741/ https://www.ncbi.nlm.nih.gov/pubmed/35154282 http://dx.doi.org/10.3389/fgene.2022.823941 |