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SCClone: Accurate Clustering of Tumor Single-Cell DNA Sequencing Data

Single-cell DNA sequencing (scDNA-seq) enables high-resolution profiling of genetic diversity among single cells and is especially useful for deciphering the intra-tumor heterogeneity and evolutionary history of tumor. Specific technical issues such as allele dropout, false-positive errors, and doub...

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Detalles Bibliográficos
Autores principales: Yu , Zhenhua, Du, Fang, Song, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830741/
https://www.ncbi.nlm.nih.gov/pubmed/35154282
http://dx.doi.org/10.3389/fgene.2022.823941