Cargando…
Elucidating the Structural Features of ABCA1 in its Heterogeneous Membrane Environment
ATP Binding Cassette Transporter A1 (ABCA1) plays an integral part in Reverse Cholesterol Transport (RCT) and is critical for maintaining lipid homeostasis. One theory of lipid efflux by the transporter (alternating access) proposes that ABCA1 harbours two different conformations that provide altern...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830745/ https://www.ncbi.nlm.nih.gov/pubmed/35155567 http://dx.doi.org/10.3389/fmolb.2021.803078 |