Transcription factor regulation of eQTL activity across individuals and tissues

Tens of thousands of genetic variants associated with gene expression (cis-eQTLs) have been discovered in the human population. These eQTLs are active in various tissues and contexts, but the molecular mechanisms of eQTL variability are poorly understood, hindering our understanding of genetic regul...

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Detalles Bibliográficos
Autores principales: Flynn, Elise D., Tsu, Athena L., Kasela, Silva, Kim-Hellmuth, Sarah, Aguet, Francois, Ardlie, Kristin G., Bussemaker, Harmen J., Mohammadi, Pejman, Lappalainen, Tuuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830792/
https://www.ncbi.nlm.nih.gov/pubmed/35100260
http://dx.doi.org/10.1371/journal.pgen.1009719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830792/
https://www.ncbi.nlm.nih.gov/pubmed/35100260
http://dx.doi.org/10.1371/journal.pgen.1009719

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