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Transcription factor regulation of eQTL activity across individuals and tissues
Tens of thousands of genetic variants associated with gene expression (cis-eQTLs) have been discovered in the human population. These eQTLs are active in various tissues and contexts, but the molecular mechanisms of eQTL variability are poorly understood, hindering our understanding of genetic regul...
Autores principales: | Flynn, Elise D., Tsu, Athena L., Kasela, Silva, Kim-Hellmuth, Sarah, Aguet, Francois, Ardlie, Kristin G., Bussemaker, Harmen J., Mohammadi, Pejman, Lappalainen, Tuuli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830792/ https://www.ncbi.nlm.nih.gov/pubmed/35100260 http://dx.doi.org/10.1371/journal.pgen.1009719 |
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