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Metformin Ameliorates Inflammation and Airway Remodeling of Experimental Allergic Asthma in Mice by Restoring AMPKα Activity

Metformin has been involved in modulating inflammatory state and inhibiting cell proliferation and angiogenesis. This study aimed to determine whether metformin alleviates airway inflammation and remodeling of experimental allergic asthma and elucidate the underlying mechanism. We sensitized and cha...

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Detalles Bibliográficos
Autores principales: Ma, Wenxian, Jin, Qiaoyan, Guo, Haiqin, Han, Xinpeng, Xu, Lingbin, Lu, Shemin, Wu, Changgui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830934/
https://www.ncbi.nlm.nih.gov/pubmed/35153777
http://dx.doi.org/10.3389/fphar.2022.780148