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Metformin Ameliorates Inflammation and Airway Remodeling of Experimental Allergic Asthma in Mice by Restoring AMPKα Activity
Metformin has been involved in modulating inflammatory state and inhibiting cell proliferation and angiogenesis. This study aimed to determine whether metformin alleviates airway inflammation and remodeling of experimental allergic asthma and elucidate the underlying mechanism. We sensitized and cha...
Autores principales: | Ma, Wenxian, Jin, Qiaoyan, Guo, Haiqin, Han, Xinpeng, Xu, Lingbin, Lu, Shemin, Wu, Changgui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830934/ https://www.ncbi.nlm.nih.gov/pubmed/35153777 http://dx.doi.org/10.3389/fphar.2022.780148 |
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