A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor

A tiny fraction of people immunized with lipid nanoparticle (LNP)-enclosed mRNA (LNP-mRNA) vaccines develop allergic symptoms following their first or subsequent vaccinations, including anaphylaxis. These reactions resemble complement (C) activation-related pseudoallergy (CARPA) to i.v. administered...

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Detalles Bibliográficos
Autores principales: Dézsi, László, Mészáros, Tamás, Kozma, Gergely, H-Velkei, Mária, Oláh, Csaba Zs., Szabó, Miklós, Patkó, Zsófia, Fülöp, Tamás, Hennies, Mark, Szebeni, Miklós, Barta, Bálint András, Merkely, Béla, Radovits, Tamás, Szebeni, János
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831099/
https://www.ncbi.nlm.nih.gov/pubmed/35146583
http://dx.doi.org/10.1007/s11357-021-00495-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831099/
https://www.ncbi.nlm.nih.gov/pubmed/35146583
http://dx.doi.org/10.1007/s11357-021-00495-y

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