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Dihydropyrimidine dehydrogenase (DPD) polymorphisms knocking on the door

Identifying polymorphisms in the dihydropyrimidine dehydrogenase (DPYD) genes is gaining importance as predictors of fluoropyrimidine-associated toxicity. The recommendation of dose adjustment for chemotherapy guided by the presence of polymorphisms of the DPYD gene can potentially improve treatment...

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Detalles Bibliográficos
Autores principales: Donadio, Mauro Daniel Spina, Carraro, Dirce Maria, Torrezan, Giovana Tardin, de Mello, Celso Abdon Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831114/
https://www.ncbi.nlm.nih.gov/pubmed/35242225
http://dx.doi.org/10.3332/ecancer.2022.1344