Cargando…

Dihydropyrimidine dehydrogenase (DPD) polymorphisms knocking on the door

Identifying polymorphisms in the dihydropyrimidine dehydrogenase (DPYD) genes is gaining importance as predictors of fluoropyrimidine-associated toxicity. The recommendation of dose adjustment for chemotherapy guided by the presence of polymorphisms of the DPYD gene can potentially improve treatment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Donadio, Mauro Daniel Spina, Carraro, Dirce Maria, Torrezan, Giovana Tardin, de Mello, Celso Abdon Lopes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cancer Intelligence 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831114/ https://www.ncbi.nlm.nih.gov/pubmed/35242225 http://dx.doi.org/10.3332/ecancer.2022.1344

Ejemplares similares

Impact of renal impairment on dihydropyrimidine dehydrogenase (DPD) phenotyping
por: Royer, B., et al.
Publicado: (2023)

Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer
por: Ferrari, Ariana, et al.
Publicado: (2019)

Expression of dihydropyrimidine dehydrogenase (DPD) and hENT1 predicts survival in pancreatic cancer
por: Elander, N. O., et al.
Publicado: (2018)

DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview
por: Paulsen, Niels Herluf, et al.
Publicado: (2022)

Study of Thymidylate Synthase (TS) and Dihydropyrimidine Dehydrogenase (DPD) Expressions on 5-Fluorouracil in Oral Squamous Cell Carcinoma
por: Akhter, Khaleda, et al.
Publicado: (2019)

Pitfalls in genetic testing: a case of a SNP in primer‐annealing region leading to allele dropout in BRCA1
por: Silva, Felipe Carneiro, et al.
Publicado: (2017)

Potential added value of combined DPYD/DPD genotyping and phenotyping to prevent severe toxicity in patients with a DPYD variant and decreased dihydropyrimidine dehydrogenase enzyme activity
por: Ockeloen, Charlotte W, et al.
Publicado: (2021)

A novel SYBR-based duplex qPCR for the detection of gene dosage: detection of an APC large deletion in a familial adenomatous polyposis patient with an unusual phenotype
por: Torrezan, Giovana Tardin, et al.
Publicado: (2012)

Knocking on EPA's door
Publicado: (1986)

Knocking on the LHC’s door
Publicado: (2008)

Dihydropyrimidine Dehydrogenase Deficiency: To Screen or Not to Screen?
por: Vogel, Wendy H., et al.
Publicado: (2020)

A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease
por: Ferreira, Elisa Napolitano, et al.
Publicado: (2016)

People who knock on the door /
por: Highsmith, Patricia, 1921-1995
Publicado: (1983)

Protoparvovirus Knocking at the Nuclear Door
por: Mäntylä, Elina, et al.
Publicado: (2017)

Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity
por: Milano, G, et al.
Publicado: (1999)

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours.
por: McLeod, H. L., et al.
Publicado: (1998)

Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer.
por: Ridge, S. A., et al.
Publicado: (1998)

Implementation of dihydropyrimidine dehydrogenase deficiency testing in Europe
por: de With, M., et al.
Publicado: (2023)

Impact of Guidelines Regarding Dihydropyrimidine Dehydrogenase (DPD) Deficiency Screening Using Uracil-Based Phenotyping on the Reduction of Severe Side Effect of 5-Fluorouracil-Based Chemotherapy: A Propension Score Analysis
por: Laures, Nicolas, et al.
Publicado: (2022)

Effect of dihydropyrimidine dehydrogenase single nucleotide polymorphisms on prognosis of breast cancer patients with chemotherapy
por: Qin, Fengxia, et al.
Publicado: (2017)

An unexpected knock on Corrigan’s secret door
por: Woywodt, Alexander
Publicado: (2010)

Epigenetics knocks on synthetic biology's door
por: Rodriguez-Escamilla, Zuemy, et al.
Publicado: (2016)

Planet earth is knocking on the doctor's door
por: Haahtela, Tari, et al.
Publicado: (2022)

Mutational spectrum of the APC and MUTYH genes and genotype–phenotype correlations in Brazilian FAP, AFAP, and MAP patients
por: Torrezan, Giovana Tardin, et al.
Publicado: (2013)

Li–Fraumeni-associated pancreatic neuroendocrine tumour and XAF1 p.Glu134Ter risk modifier variant
por: Riechelmann, Rachel P, et al.
Publicado: (2022)

Knock, knock, knocking on Europe’s door: Threat of leishmaniasis in Europe with a focus on Turkey
por: Tunalı, Varol, et al.
Publicado: (2023)

Prognostic significance of dihydropyrimidine dehydrogenase expression in breast cancer
por: Horiguchi, J, et al.
Publicado: (2002)

Undetected Toxicity Risk in Pharmacogenetic Testing for Dihydropyrimidine Dehydrogenase
por: Falvella, Felicia Stefania, et al.
Publicado: (2015)

A ferredoxin-dependent dihydropyrimidine dehydrogenase in Clostridium chromiireducens
por: Wang, Feifei, et al.
Publicado: (2020)

Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase
por: Kang, Jihyun, et al.
Publicado: (2021)

Characterization of Potential Melanoma Predisposition Genes in High-Risk Brazilian Patients
por: Soares de Sá, Bianca Costa, et al.
Publicado: (2023)

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?
por: Del Re, Marzia, et al.
Publicado: (2010)

The Role of Dihydropyrimidine Dehydrogenase and Thymidylate Synthase Polymorphisms in Fluoropyrimidine-Based Cancer Chemotherapy in an Iranian Population
por: Abbasian, Mohammad Hadi, et al.
Publicado: (2020)

The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilian cohort: A preliminary study
por: da Costa, Leonardo Tomiatti, et al.
Publicado: (2021)

Dihydropyrimidine dehydrogenase deficiency as a cause of fatal 5-Fluorouracil toxicity
por: Fidai, Shiraz S., et al.
Publicado: (2018)

A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity
por: Nagaharu, Keiki, et al.
Publicado: (2016)

Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy
por: Diasio, Robert B., et al.
Publicado: (2022)

Strong Association of a Common Dihydropyrimidine Dehydrogenase Gene Polymorphism with Fluoropyrimidine-Related Toxicity in Cancer Patients
por: Gross, Eva, et al.
Publicado: (2008)

BAP1 tumor predisposition syndrome case report: pathological and clinical aspects of BAP1-inactivated melanocytic tumors (BIMTs), including dermoscopy and confocal microscopy
por: Soares de Sá, Bianca Costa, et al.
Publicado: (2019)

Characterization of genetic predisposition to molecular subtypes of breast cancer in Brazilian patients
por: Paixão, Daniele, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nkj86ht61ff0nqrj48bg8goj86