Toll-Like Receptor- and Protein Kinase R-Induced Type I Interferon Sustains Infection of Leishmania donovani in Macrophages

Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis, provoking liver and spleen tissue destruction that is lethal unless treated. The parasite replicates in macrophages and modulates host microbicidal responses. We have previously reported that neutrophil elastase (NE) is...

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Detalles Bibliográficos
Autores principales: Dias, Bruna T., Goundry, Amy, Vivarini, Aislan C., Costa, Tatiana F. R., Mottram, Jeremy C., Lopes, Ulisses G., Lima, Ana Paula C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831251/
https://www.ncbi.nlm.nih.gov/pubmed/35154115
http://dx.doi.org/10.3389/fimmu.2022.801182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831251/
https://www.ncbi.nlm.nih.gov/pubmed/35154115
http://dx.doi.org/10.3389/fimmu.2022.801182

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