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Binding site identification of G protein-coupled receptors through a 3D Zernike polynomials-based method: application to C. elegans olfactory receptors

Studying the binding processes of G protein-coupled receptors (GPCRs) proteins is of particular interest both to better understand the molecular mechanisms that regulate the signaling between the extracellular and intracellular environment and for drug design purposes. In this study, we propose a ne...

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Detalles Bibliográficos
Autores principales: Di Rienzo, Lorenzo, De Flaviis, Luca, Ruocco, Giancarlo, Folli, Viola, Milanetti, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831295/
https://www.ncbi.nlm.nih.gov/pubmed/34977999
http://dx.doi.org/10.1007/s10822-021-00434-1