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Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart

Myostatin (MSTN) is a primary negative regulator of skeletal muscle mass and causes multiple metabolic changes. However, whether MSTN mutation affects heart morphology and physiology remains unclear. Myostatin mutation (MT) had no effect on cattle cardiac muscle in histological examination, but in b...

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Detalles Bibliográficos
Autores principales: Gu, Mingjuan, Zhou, Xinyu, Zhu, Lin, Gao, Yajie, Gao, Li, Bai, Chunling, Yang, Lei, Li, Guangpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831326/
https://www.ncbi.nlm.nih.gov/pubmed/35155444
http://dx.doi.org/10.3389/fcell.2021.774185