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Early differential responses elicited by BRAF(V600E) in adult mouse models

The BRAF gene is frequently mutated in cancer. The most common genetic mutation is a single nucleotide transition which gives rise to a constitutively active BRAF kinase (BRAF(V600E)) which in turn sustains continuous cell proliferation. The study of BRAF(V600E) murine models has been mainly focused...

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Detalles Bibliográficos
Autores principales: Bosso, Giuseppe, Lanuza-Gracia, Pablo, Piñeiro-Hermida, Sergio, Yilmaz, Merve, Serrano, Rosa, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831492/
https://www.ncbi.nlm.nih.gov/pubmed/35145078
http://dx.doi.org/10.1038/s41419-022-04597-z