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Early differential responses elicited by BRAF(V600E) in adult mouse models
The BRAF gene is frequently mutated in cancer. The most common genetic mutation is a single nucleotide transition which gives rise to a constitutively active BRAF kinase (BRAF(V600E)) which in turn sustains continuous cell proliferation. The study of BRAF(V600E) murine models has been mainly focused...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831492/ https://www.ncbi.nlm.nih.gov/pubmed/35145078 http://dx.doi.org/10.1038/s41419-022-04597-z |