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Cotranslational N-degron masking by acetylation promotes proteome stability in plants

N-terminal protein acetylation (NTA) is a prevalent protein modification essential for viability in animals and plants. The dominant executor of NTA is the ribosome tethered N(α)-acetyltransferase A (NatA) complex. However, the impact of NatA on protein fate is still enigmatic. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Linster, Eric, Forero Ruiz, Francy L., Miklankova, Pavlina, Ruppert, Thomas, Mueller, Johannes, Armbruster, Laura, Gong, Xiaodi, Serino, Giovanna, Mann, Matthias, Hell, Rüdiger, Wirtz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831508/
https://www.ncbi.nlm.nih.gov/pubmed/35145090
http://dx.doi.org/10.1038/s41467-022-28414-5