GLI transcriptional repression is inert prior to Hedgehog pathway activation

The Hedgehog (HH) pathway regulates a spectrum of developmental processes through the transcriptional mediation of GLI proteins. GLI repressors control tissue patterning by preventing sub-threshold activation of HH target genes, presumably even before HH induction, while lack of GLI repression activ...

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Detalles Bibliográficos
Autores principales: Lex, Rachel K., Zhou, Weiqiang, Ji, Zhicheng, Falkenstein, Kristin N., Schuler, Kaleigh E., Windsor, Kathryn E., Kim, Joseph D., Ji, Hongkai, Vokes, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831537/
https://www.ncbi.nlm.nih.gov/pubmed/35145123
http://dx.doi.org/10.1038/s41467-022-28485-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831537/
https://www.ncbi.nlm.nih.gov/pubmed/35145123
http://dx.doi.org/10.1038/s41467-022-28485-4

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