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Raster plots machine learning to predict the seizure liability of drugs and to identify drugs

In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods used to predict seizure and toxicity liability as well as dru...

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Detalles Bibliográficos
Autores principales: Matsuda, N., Odawara, A., Kinoshita, K., Okamura, A., Shirakawa, T., Suzuki, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831568/
https://www.ncbi.nlm.nih.gov/pubmed/35145132
http://dx.doi.org/10.1038/s41598-022-05697-8