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IκB-ζ signaling promotes chondrocyte inflammatory phenotype, senescence, and erosive joint pathology

Osteoarthritis is a joint disease characterized by a poorly-defined inflammatory response that does not encompass a massive immune cell infiltration yet contributes to cartilage degradation and loss of joint mobility, suggesting a chondrocyte intrinsic inflammatory response. Using primary chondrocyt...

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Detalles Bibliográficos
Autores principales: Arra, Manoj, Swarnkar, Gaurav, Alippe, Yael, Mbalaviele, Gabriel, Abu-Amer, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831569/
https://www.ncbi.nlm.nih.gov/pubmed/35145063
http://dx.doi.org/10.1038/s41413-021-00183-9