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IκB-ζ signaling promotes chondrocyte inflammatory phenotype, senescence, and erosive joint pathology
Osteoarthritis is a joint disease characterized by a poorly-defined inflammatory response that does not encompass a massive immune cell infiltration yet contributes to cartilage degradation and loss of joint mobility, suggesting a chondrocyte intrinsic inflammatory response. Using primary chondrocyt...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831569/ https://www.ncbi.nlm.nih.gov/pubmed/35145063 http://dx.doi.org/10.1038/s41413-021-00183-9 |