Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis

Copy number alterations (CNAs) are pivotal genetic events in triple-negative breast cancer (TNBC). Here, our integrated copy number and transcriptome analysis of 302 TNBC patients reveals that gene alpha-endosulfine (ENSA) exhibits recurrent amplification at the 1q21.3 region and is highly expressed...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Yu, Ge, Jing-Yu, Zhu, Si-Yuan, Shao, Zhi-Ming, Yu, Ke-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831589/
https://www.ncbi.nlm.nih.gov/pubmed/35145111
http://dx.doi.org/10.1038/s41467-022-28452-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831589/
https://www.ncbi.nlm.nih.gov/pubmed/35145111
http://dx.doi.org/10.1038/s41467-022-28452-z

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