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Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor

The intracellular domain (ICD) of Cys-loop receptors mediates diverse functions. To date, no structure of a full-length ICD is available due to challenges stemming from its dynamic nature. Here, combining nuclear magnetic resonance (NMR) and electron spin resonance experiments with Rosetta computati...

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Detalles Bibliográficos
Autores principales: Bondarenko, Vasyl, Wells, Marta M., Chen, Qiang, Tillman, Tommy S., Singewald, Kevin, Lawless, Matthew J., Caporoso, Joel, Brandon, Nicole, Coleman, Jonathan A., Saxena, Sunil, Lindahl, Erik, Xu, Yan, Tang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831596/
https://www.ncbi.nlm.nih.gov/pubmed/35145092
http://dx.doi.org/10.1038/s41467-022-28400-x