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Defining molecular glues with a dual-nanobody cannabidiol sensor

“Molecular glue” (MG) is a term coined to describe the mechanism of action of the plant hormone auxin and subsequently used to characterize synthetic small molecule protein degraders exemplified by immune-modulatory imide drugs (IMiDs). Prospective development of MGs, however, has been hampered by i...

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Detalles Bibliográficos
Autores principales: Cao, Shiyun, Kang, Shoukai, Mao, Haibin, Yao, Jiayu, Gu, Liangcai, Zheng, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831599/
https://www.ncbi.nlm.nih.gov/pubmed/35145136
http://dx.doi.org/10.1038/s41467-022-28507-1