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Defining molecular glues with a dual-nanobody cannabidiol sensor
“Molecular glue” (MG) is a term coined to describe the mechanism of action of the plant hormone auxin and subsequently used to characterize synthetic small molecule protein degraders exemplified by immune-modulatory imide drugs (IMiDs). Prospective development of MGs, however, has been hampered by i...
Autores principales: | Cao, Shiyun, Kang, Shoukai, Mao, Haibin, Yao, Jiayu, Gu, Liangcai, Zheng, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831599/ https://www.ncbi.nlm.nih.gov/pubmed/35145136 http://dx.doi.org/10.1038/s41467-022-28507-1 |
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