Glutaredoxin 1 controls monocyte reprogramming during nutrient stress and protects mice against obesity and atherosclerosis in a sex-specific manner

High-calorie diet-induced nutrient stress promotes thiol oxidative stress and the reprogramming of blood monocytes, giving rise to dysregulated, obesogenic, proatherogenic monocyte-derived macrophages. We report that in chow-fed, reproductively senescent female mice but not in age-matched male mice,...

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Detalles Bibliográficos
Autores principales: Ahn, Yong Joo, Wang, Luxi, Tavakoli, Sina, Nguyen, Huynh Nga, Short, John D., Asmis, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831602/
https://www.ncbi.nlm.nih.gov/pubmed/35145079
http://dx.doi.org/10.1038/s41467-022-28433-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831602/
https://www.ncbi.nlm.nih.gov/pubmed/35145079
http://dx.doi.org/10.1038/s41467-022-28433-2

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