Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice

Statins play a major role in reducing circulating cholesterol levels and are widely used to prevent coronary artery disease. Although they are recently confirmed to up-regulate mitophagy, little is known about the molecular mechanisms and its effect on endothelial progenitor cell (EPC). Here, we exp...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Sun, Mengjia, Cheng, Ran, Tan, Hu, Liu, Chuan, Chen, Renzheng, Zhang, Jihang, Yang, Yuanqi, Gao, Xubin, Huang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831604/
https://www.ncbi.nlm.nih.gov/pubmed/35145192
http://dx.doi.org/10.1038/s42003-022-03081-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831604/
https://www.ncbi.nlm.nih.gov/pubmed/35145192
http://dx.doi.org/10.1038/s42003-022-03081-w

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