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Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models

Acute respiratory distress syndrome (ARDS) is triggered by various aetiological factors such as trauma, sepsis and respiratory viruses including SARS-CoV-2 and influenza A virus. Immune profiling of severe COVID-19 patients has identified a complex pattern of cytokines including granulocyte macropha...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Tumes, Damon J., Hercus, Timothy R., Yip, K. H., Aloe, Christian, Vlahos, Ross, Lopez, Angel F., Wilson, Nick, Owczarek, Catherine M., Bozinovski, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831609/
https://www.ncbi.nlm.nih.gov/pubmed/35145069
http://dx.doi.org/10.1038/s41419-022-04589-z