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Exploring synthetic biology for the development of a sensor cell line for automated bioprocess control

Unfavorable process conditions lead to adverse cultivation states, limited cell growth and thus hamper biotherapeutic protein production. Oxygen deficiency or hyperosmolality are among the most critical process conditions and therefore require continuous monitoring. We established a novel sensor CHO...

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Detalles Bibliográficos
Autores principales: Zeh, Nikolas, Bräuer, Melina, Raab, Nadja, Handrick, René, Otte, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831625/
https://www.ncbi.nlm.nih.gov/pubmed/35145179
http://dx.doi.org/10.1038/s41598-022-06272-x