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Exploring synthetic biology for the development of a sensor cell line for automated bioprocess control
Unfavorable process conditions lead to adverse cultivation states, limited cell growth and thus hamper biotherapeutic protein production. Oxygen deficiency or hyperosmolality are among the most critical process conditions and therefore require continuous monitoring. We established a novel sensor CHO...
Autores principales: | Zeh, Nikolas, Bräuer, Melina, Raab, Nadja, Handrick, René, Otte, Kerstin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831625/ https://www.ncbi.nlm.nih.gov/pubmed/35145179 http://dx.doi.org/10.1038/s41598-022-06272-x |
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