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Serotonin 5-HT(2C) receptor knockout in mice attenuates fear responses in contextual or cued but not compound context-cue fear conditioning
Previous findings have proposed that drugs targeting 5-HT(2C) receptors could be promising candidates in the treatment of trauma- and stress-related disorders. However, the reduction of conditioned freezing observed in 5-HT(2C) receptor knock-out (KO) mice in previous studies could alternatively be...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831648/ https://www.ncbi.nlm.nih.gov/pubmed/35145065 http://dx.doi.org/10.1038/s41398-022-01815-2 |