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Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer

BACKGROUND: Dendritic cells (DCs) are central for the initiation and regulation of innate and adaptive immunity in the tumor microenvironment. As such, many kinds of DC-targeted vaccines have been developed to improve cancer immunotherapy in numerous clinical trials. Targeted delivery of antigens an...

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Detalles Bibliográficos
Autores principales: Huang, Lanxiang, Rong, Yuan, Tang, Xuan, Yi, Kezhen, Qi, Peng, Hou, Jinxuan, Liu, Weihuang, He, Yuan, Gao, Xing, Yuan, Chunhui, Wang, Fubing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831689/
https://www.ncbi.nlm.nih.gov/pubmed/35148751
http://dx.doi.org/10.1186/s12943-022-01515-x